MI5 security officer Eve Polastri is bored in her job and yearns for a more exciting life. When a Russian politician is murdered, Eve is tasked with protecting the only witness and soon finds herself on a collision course with a violent and extraordinary assassin.
In the aftermath of her recent assignment, Villanelle is ordered to take a break. Never one to do as she’s told, she goes ahead with her next mission regardless. Eve is given a dream opportunity to join a secret MI6 unit tracking Villanelle and the shady organisation she works for.
When Villanelle kills a Chinese Colonel at a kink clinic in Berlin, Eve and Bill travel out to investigate. While Eve and Bill chase up a number of promising leads, Villanelle enjoys the cat and mouse of their proximity. But as they draw closer, Eve comes to realise that this is much more than a game.
Intel from Berlin points to the existence of a mole, prompting Eve to undertake her first surveillance operation. Villanelle is sent to England to eliminate a member of British Intelligence. Eve, in emotional turmoil, now knows how high the stakes are.
Having survived a terrifying close call with Villanelle, Eve now has the mole ensconced in a safe house and is buzzing. They have an exciting opportunity to glean information and crack this thing open.
Eve and Carolyn head out to Moscow to negotiate access to a female assassin that could hold the key to the organization that runs Villanelle. Villanelle is smuggled into the same Russian jail.
Tensions are running high as the situation in Moscow escalates, and Eve starts to question who she can trust. Despite the danger, with her sights firmly set on Villanelle, Eve goes rogue. With both women under pressure, the stakes are higher than ever.
Eve is reeling from her act of violence against Villanelle and doesn’t know whether she is alive or dead. A paranoid and severely injured Villanelle manages to get herself to the hospital for treatment. Carolyn approaches Eve with an intriguing opportunity.
Carolyn introduces Eve to her new team before Eve briefs them on the Villanelle case. Villanelle, needing to lie low while she recovers, finds a good Samaritan to take her in and care for her.
Villanelle's circumstances are looking bleak. Eve makes a dangerous deal with an old acquaintance. Villanelle is surprised when she is approached by a figure from her past.
After the discovery of another dead body, Eve and her new team make a break in their case. Villanelle decides to take matters into her own hands on a trip to Amsterdam. Carolyn is called in to face the music with her boss.
The MI6 team make a pact with the devil in order to get information from The Ghost.
Villanelle uses her unrivaled infiltration skills to immerse herself in the world of a new target.
Eve may have worrying competition for Villanelle's affections.